http://simhq.com/forum/ubbthreads.php/topics/2681178/1.htmlSummary:
*An E6600 Overclocked to 3.4 GHz, 3gigs of RAM, along with an nVidia 8800GTS/GTX should run Rise of Flight "ok up to 1920x1200".
*Rise of Flight is nicely multithreaded. VikS says "two/four cores will work. Actually we have exact numbers of trials. . .Core Quad 9450 @ 2,66 vs Core Duo E6750 @ 2,66. . .and core quad works 30-40% faster than core duo with ROF" (If that ends up being the case it will be pretty impressive - though good Dual core CPUs run much higher overclocks than a Quad so it might end up a tossup.)
*Rise of Flight is a little faster running under WInXP than Vista, at least for a 32bit OS.